Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1381
Gene Name: CDGSH iron sulfur domain 2
Gene Symbol: cisd2
Previous Name: zgc:64148
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64148]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la013675Tg
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Wolfram syndrome 2 604928
GENE ONTOLOGY
Ontology GO Term
Biological Process mitochondrion degradation (more)
Cellular Component endoplasmic reticulum membrane (more)
Molecular Function 2 iron, 2 sulfur cluster binding (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR018967 (1)
  • InterPro:IPR019610 (1)
  • Pfam:PF09360 (1)
  • Pfam:PF10660 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cisd2-001 (1) 1312
    cisd2-002 (1) 679
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM cisd2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cisd2 Contained in: [BAC] DKEY-162B23 (1)
    cisd2 Encodes: [cDNA] MGC:64148 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200383 (1) 1320 bp
    Genomic GenBank:CR388005 (1) 197480 bp
    Select Tool
    Polypeptide UniProtKB:Q7T326 (1) 135 aa
    Sequence Clusters UniGene:77441 (1)
    Sequence Information (all 11)
    OTHER cisd2 GENE PAGES
  • Gene:393354 (1)
  • VEGA:OTTDARG00000027160 (1)
  • Ensembl(Zv9):ENSDARG00000052703 (1)
  • MAPPING INFORMATION
    Chr: 1 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA CL
    Zebrafish cisd2 1  
    Human CISD2 4 (4q24)
  • OMIM:611507
  • Gene:493856
  • CITATIONS (19)