ZFIN ID: ZDB-GENE-040426-1367
Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1b (glutamate binding)
Gene Symbol: grinab    Nomenclature History

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Previous Names: grina, tmbim3 (1), zgc:64102

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Involved in negative regulation of apoptotic process and negative regulation of neuron death. Predicted to localize to the integral component of membrane. Is expressed in eye; head; nervous system; and spinal cord. Orthologous to human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).
Genome Resources: Alliance (1),  Gene:394183 (1),  Ensembl(GRCz11):ENSDARG00000052746 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64102]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa28759 Point Mutation Unknown Splice Site ENU
sa36273 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-grinab N/A 2
    DISEASE ASSOCIATED WITH grinab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grinab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of apoptotic process (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR006214 Bax inhibitor 1-related
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grinab-201 (1)    Ensembl 1657
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grinab No data available
    MARKER RELATIONSHIPS
    grinab Contained in: [BAC] CH211-214L23 (1), DKEY-199L17 (1) (order this)
    grinab Encodes: [cDNA] MGC:64102 (1), MGC:174823 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201208 (1) 1570 nt
    Genomic GenBank:CR759845 (1) 181187 nt
    Select Tool
    Polypeptide UniProtKB:A7MCR2 (1) 337 aa
    Sequence Information (all 21)
    ORTHOLOGY for grinab ( Chr: 16 )
    CITATIONS (18)