ZFIN ID: ZDB-GENE-040426-1361
Gene Name: lipase, hepatic a
Gene Symbol: lipca
Sequence Ontology ID : SO:0000704

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Previous Names: lipc, zgc:64081

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have triglyceride lipase activity; involved in response to hormone; predicted to localize to the extracellular region; orthologous to human LIPC (lipase C, hepatic type).
GENE EXPRESSION
All Expression Data: 9 figures from 5 publications
Directly Submitted Expression Data: 2 figures (2 images) from Thisse et al., 2004 [MGC:64081]
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016069Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa189 Point Mutation Unknown Unknown ENU
    sa12401 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20975 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lipca HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    type 2 diabetes mellitus {Diabetes mellitus, noninsulin-dependent} 125853
    Hepatic lipase deficiency 614025
    [High density lipoprotein cholesterol level QTL 12] 612797
    DISEASE ASSOCIATED WITH lipca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hormone (more)
    Cellular Component extracellular region (more)
    Molecular Function carboxylic ester hydrolase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000734 (1)
  • InterPro:IPR001024 (1)
  • InterPro:IPR002333 (1)
  • InterPro:IPR013818 (1)
  • InterPro:IPR016272 (1)
  • InterPro:IPR029058 (1)
  • InterPro:IPR033906 (1)
  • InterPro:IPR036392 (1)
  • PROSITE:PS50095 (1)
  • Pfam:PF00151 (1)
  • Pfam:PF01477 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lipca-001 (1) 1923
    ncRNA lipca-002 (1) 1127
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lipca No data available
    MARKER RELATIONSHIPS
    lipcaContained in: [BAC] DKEY-261O24 (1) (order this)
    lipcaEncodes: [cDNA] MGC:64081 (1) (order this), MGC:191138 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201022 (1) 1733bp
    Genomic GenBank:BX957301 (1) 64006bp
    Select Tool
    Polypeptide UniProtKB:F1QA22 (1) 514aa
    Sequence Clusters UniGene:132354 (1)
    Sequence Information (all 15)
    OTHER lipca GENE PAGES
  • Alliance (1)
  • Gene:393997 (1)
  • VEGA:OTTDARG00000020178 (1)
  • Ensembl(GRCz11):ENSDARG00000053476 (2)
  • ORTHOLOGY for lipca (Chr: 7)
    CITATIONS (33)