Gene

cul4a

ID

ZDB-GENE-040426-1357

Name

cullin 4A

Symbol

cul4a Nomenclature History

Previous Names

zgc:64071

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable ubiquitin protein ligase binding activity. Involved in erythrocyte development. Acts upstream of or within embryonic pectoral fin morphogenesis; heart development; and otic vesicle morphogenesis. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Is expressed in brain; heart; and pectoral fin. Orthologous to human CUL4A (cullin 4A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:64071 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 11 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cul4a Human Ortholog

No data available

Associated With cul4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR016157	Cullin, conserved site
Domain	IPR001373	Cullin, N-terminal
Domain	IPR016158	Cullin homology domain
Domain	IPR019559	Cullin protein, neddylation domain
Family	IPR045093	Cullin
Homologous_superfamily	IPR016159	Cullin repeat-like-containing domain superfamily
Homologous_superfamily	IPR036317	Cullin homology domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily