Gene

prkcba

ID
ZDB-GENE-040426-1354
Name
protein kinase C, beta a
Symbol
prkcba Nomenclature History
Previous Names
  • prkcb1l
  • zgc:64063 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Is expressed in several structures, including brain; forebrain neural keel; otic placode; pectoral fin musculature; and pronephros. Orthologous to human PRKCB (protein kinase C beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkcba Human Ortholog
No data available
Associated With prkcba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000008 C2 domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR020454 Diacylglycerol/phorbol-ester binding
Family IPR014375 Protein kinase C, alpha/beta/gamma types
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain C2 domain superfamily Diacylglycerol/phorbol-ester binding Protein kinase, ATP binding site Protein kinase C, alpha/beta/gamma types Protein kinase C-like, phorbol ester/diacylglycerol-binding domain Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:A0A2R8RKD1 660
UniProtKB:Q7T2C5 668
UniProtKB:E9QEK0 176
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations