ZFIN ID: ZDB-GENE-040426-1354
Gene Name: protein kinase C, beta a
Gene Symbol: prkcba    Nomenclature History

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Previous Names: prkcb1l, zgc:64063 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Is expressed in several structures, including brain; forebrain neural keel; otic placode; pectoral fin musculature; and pronephros. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and lung non-small cell carcinoma. Orthologous to human PRKCB (protein kinase C beta).
Genome Resources: Alliance (1),  Gene:100006675 (1),  Ensembl(GRCz11):ENSDARG00000008723 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1978 Point Mutation Unknown Premature Stop ENU
sa11204 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31191 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32592 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko176a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko176b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-prkcba 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prkcba HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prkcba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Molecular Function ATP binding (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prkcba-201 (1)    Ensembl 2481
    prkcba-202 (1)    Ensembl 1155
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prkcba No data available
    MARKER RELATIONSHIPS
    prkcba Contained in: [BAC] CH73-191K20 (1), CH211-14K19 (1)
    prkcba Encodes: [cDNA] MGC:64063 (1), MGC:198407 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201029 (1) 2561 nt
    Genomic GenBank:BX004779 (1) 196036 nt
    Select Tool
    Polypeptide UniProtKB:Q7T2C5 (1) 668 aa
    Sequence Information (all 16)
    ORTHOLOGY for prkcba ( Chr: 1 )
    CITATIONS (23)