Gene

rab7a

ID
ZDB-GENE-040426-1352
Name
RAB7a, member RAS oncogene family
Symbol
rab7a Nomenclature History
Previous Names
  • rab7 (1)
  • zgc:64058
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have GTP binding activity and GTPase activity. Involved in endosomal transport. Localizes to late endosome. Is expressed in neural crest. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2B. Orthologous to human RAB7A (RAB7A, member RAS oncogene family).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rab7a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 2B Alliance Charcot-Marie-Tooth disease, type 2B 600882
Associated With rab7a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005225 Small GTP-binding protein domain
Family IPR001806 Small GTPase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTP-binding protein domain
UniProtKB:Q7T2C6 207
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations