Gene

myo1eb

ID
ZDB-GENE-040426-1347
Name
myosin IEb
Symbol
myo1eb Nomenclature History
Previous Names
  • zgc:64042
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity; actin-dependent ATPase activity; and microfilament motor activity. Involved in glomerular filtration and glomerulus development. Predicted to localize to several cellular components, including actin cytoskeleton; microvillus; and vesicle. Is expressed in several structures, including EVL; ectoderm; epidermis; peripheral olfactory organ; and pharynx. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Orthologous to human MYO1E (myosin IE).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myo1eb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
focal segmental glomerulosclerosis 6 Alliance Glomerulosclerosis, focal segmental, 6 614131
Associated With myo1eb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR001609 Myosin head, motor domain
Domain IPR010926 Class I myosin tail homology domain
Domain IPR035507 Unconventional myosin-Ie/If, SH3 domain
Domain IPR036072 Class I myosin, motor domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Class I myosin, motor domain Class I myosin tail homology domain Kinesin motor domain superfamily Myosin head, motor domain P-loop containing nucleoside triphosphate hydrolase SH3 domain SH3-like domain superfamily Unconventional myosin-Ie/If, SH3 domain
UniProtKB:A0A2R8QAL9 1090
UniProtKB:Q6PFT4 1096
UniProtKB:F1QJK0 1096
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations