ZFIN ID: ZDB-GENE-040426-1339
Gene Name: hydroxysteroid (17-beta) dehydrogenase 3
Gene Symbol: hsd17b3
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:64019 (1)

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(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits testosterone 17-beta-dehydrogenase (NADP+) activity; involved in androgen biosynthetic process; localizes to the endoplasmic reticulum; orthologous to human HSD17B3 (hydroxysteroid 17-beta  ...
GENE EXPRESSION
All Expression Data: 7 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:64019]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hsd17b3 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Pseudohermaphroditism, male, with gynecomastia 264300
DISEASE ASSOCIATED WITH hsd17b3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process androgen biosynthetic process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function testosterone 17-beta-dehydrogenase (NADP+) activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002347 (1)
  • InterPro:IPR020904 (1)
  • InterPro:IPR033281 (1)
  • InterPro:IPR036291 (1)
  • PROSITE:PS00061 (1)
  • Pfam:PF00106 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA hsd17b3-003 (1) 655
    mRNA hsd17b3-201 (1) 2116
    hsd17b3-203 (1) 2145
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hsd17b3 No data available
    MARKER RELATIONSHIPS
    hsd17b3Contained in: [BAC] CH211-248D20 (1) (order this)
    hsd17b3Encodes: [cDNA] MGC:64019 (1) (order this), MGC:193009 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200364 (1) 2132bp
    Genomic GenBank:CR376747 (1) 153394bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QE67 (1) 307aa
    Sequence Clusters UniGene:88378 (1)
    Sequence Information (all 20)
    OTHER hsd17b3 GENE PAGES
  • Alliance (1)
  • Gene:393335 (1)
  • VEGA:OTTDARG00000034547 (1)
  • ORTHOLOGY for hsd17b3 (Chr: 8)
    CITATIONS (66)