ZFIN ID: ZDB-GENE-040426-1332
Gene Name: arrestin, beta 2b
Gene Symbol: arrb2b    Nomenclature History

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Previous Names: arrb2, ARRB2b2 (1), zgc:64007

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have angiotensin receptor binding activity. Involved in muscle organ development; regulation of receptor recycling; and regulation of signal transduction. Predicted to localize to cytoplasm. Is expressed in several structures, including alar plate midbrain region; axis; brain; vasculature; and ventral mesoderm. Orthologous to human ARRB2 (arrestin beta 2).
Genome Resources: Alliance (1),  Gene:394099 (1),  Ensembl(GRCz11):ENSDARG00000011545 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 5 publications
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [MGC:64007]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025918Tg Transgenic Insertion Unknown Unknown DNA
sa38610 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40890 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arrb2b N/A 5
    MO2-arrb2b N/A 1
    MO3-arrb2b N/A 1
    DISEASE ASSOCIATED WITH arrb2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arrb2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of chemokine activity (more)
    Cellular Component cytoplasm (more)
    Molecular Function angiotensin receptor binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arrb2b-201 (1)    Ensembl 4613
    ncRNA arrb2b-002 (1)    Ensembl 719
    arrb2b-003 (1)    Ensembl 636
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arrb2b No data available
    MARKER RELATIONSHIPS
    arrb2b Contained in: [BAC] DKEY-6N21 (1) (order this)
    arrb2b Encodes: [cDNA] MGC:64007 (1), MGC:191683 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201124 (1) 2656 nt
    Genomic GenBank:BX005022 (1) 217582 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7T2D2 (1) 408 aa
    Sequence Information (all 19)
    ORTHOLOGY for arrb2b ( Chr: 7 )
    CITATIONS (37)