ZFIN ID: ZDB-GENE-040426-1324
Gene Name: derlin 3
Gene Symbol: derl3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:63991

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have misfolded protein binding activity and ubiquitin-specific protease binding activity. Predicted to be involved in endoplasmic reticulum unfolded protein response and ubiquitin-dependent ERAD pathway. Predicted to localize to Hrd1p ubiquitin ligase ERAD-L complex and integral component of endoplasmic reticulum membrane. Orthologous to human DERL3 (derlin 3).
Genome Resources: Alliance (1),  Gene:393877 (1),  Ensembl(GRCz11):ENSDARG00000033871 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16948 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH derl3 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH derl3 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process endoplasmic reticulum unfolded protein response (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function misfolded protein binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA derl3-201 (1)    Ensembl 1741
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM derl3 No data available
MARKER RELATIONSHIPS
derl3 Contained in: [BAC] CH211-42D10 (1)
derl3 Encodes: [cDNA] MGC:63991 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200903 (1) 1865 nt
Genomic GenBank:BX640478 (1) 191201 nt
Select Tool
Polypeptide UniProtKB:A0A0R4IYC6 (1) 247 aa
Sequence Information (all 11)
ORTHOLOGY for derl3 ( Chr: 8 )
CITATIONS (15)