Gene
ptger2a
- ID
- ZDB-GENE-040426-1321
- Name
- prostaglandin E receptor 2a (subtype EP2)
- Symbol
- ptger2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits prostaglandin E receptor activity. Involved in embryonic liver development; exocrine pancreas development; and pronephros development. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Is expressed in several structures, including endoderm; hematopoietic stem cell; intermediate mesoderm; liver; and pleuroperitoneal region. Orthologous to human PTGER2 (prostaglandin E receptor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63974 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| asthma, nasal polyps, and aspirin intolerance | Alliance | {Asthma, aspirin-induced, susceptibility to} | 208550 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Prostacyclin (prostanoid IP) receptor | Prostanoid receptor |
|---|---|---|---|---|---|
|
UniProtKB:Q6PFT8
|
281 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ptger2a-201
(1)
|
Havana | 2369 nt | |
| mRNA |
ptger2a-202
(1)
|
Havana | 1339 nt |
Interactions and Pathways
No data available
Plasmids
No data available