ZFIN ID: ZDB-GENE-040426-1319
Gene Name: PR domain containing 9
Gene Symbol: prdm9    Nomenclature History

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Previous Name: zgc:63970

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have DNA binding activity; histone-lysine N-methyltransferase activity; and protein homodimerization activity. Predicted to be involved in several processes, including histone lysine methylation; meiosis I; and positive regulation of histone methylation. Predicted to colocalize with histone methyltransferase complex. Orthologous to human PRDM9 (PR/SET domain 9).
Genome Resources: Alliance (1),  Gene:393876 (1),  Ensembl(GRCz11):ENSDARG00000005382 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63970]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012099Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1923 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-prdm9 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prdm9 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prdm9 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process double-strand break repair involved in meiotic recombination (more)
    Cellular Component nucleus (more)
    Molecular Function histone methyltransferase activity (H3-K36 specific) (more)
    GO Terms (all 29)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prdm9-201 (1)    Ensembl 2918
    prdm9-202 (1)    Ensembl 453
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prdm9 No data available
    MARKER RELATIONSHIPS
    prdm9 Contained in: [BAC] DKEY-42B22 (order this)
    prdm9 Encodes: [cDNA] MGC:63970 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200902 (1) 2913 nt
    Genomic GenBank:CR456629 (1) 238288 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6P2A1 (1) 853 aa
    Sequence Information (all 12)
    ORTHOLOGY for prdm9 ( Chr: 12 )
    CITATIONS (27)