ZFIN ID: ZDB-GENE-040426-1312
Gene Name: endoplasmic reticulum oxidoreductase 1 alpha
Gene Symbol: ero1a    Nomenclature History

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Previous Names: ero1l, zgc:63959

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have protein disulfide isomerase activity and protein disulfide oxidoreductase activity. Predicted to be involved in protein folding in endoplasmic reticulum. Predicted to localize to the endoplasmic reticulum membrane. Orthologous to human ERO1A (endoplasmic reticulum oxidoreductase 1 alpha).
Genome Resources: Alliance (1),  Gene:393321 (1),  Ensembl(GRCz11):ENSDARG00000015228 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63959]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32137 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36359 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ero1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ero1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR007266 Endoplasmic reticulum oxidoreductin 1
    Homologous_superfamily IPR037192 ERO1-like superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ero1a-203 (1)    Ensembl 2053
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ero1a No data available
    MARKER RELATIONSHIPS
    ero1a Contained in: [BAC] CH211-84M6 (1)
    ero1a Encodes: [cDNA] MGC:63959 (1), MGC:192698 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200350 (1) 1767 nt
    Genomic GenBank:CR387921 (1) 187568 nt
    Select Tool
    Polypeptide UniProtKB:B2GSQ9 (1) 489 aa
    Sequence Information (all 18)
    ORTHOLOGY for ero1a ( Chr: 17 )
    CITATIONS (21)