ZFIN ID: ZDB-GENE-040426-1272
Gene Name: damage-specific DNA binding protein 1
Gene Symbol: ddb1    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:63840

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have damaged DNA binding activity. Involved in negative regulation of apoptotic process and regulation of cell cycle process. Predicted to localize to cullin-RING ubiquitin ligase complex and nucleus. Is expressed in blastomere; endoderm; nervous system; pharyngeal arch; and somite. Orthologous to human DDB1 (damage specific DNA binding protein 1).
Genome Resources: Alliance (1),  Gene:393599 (1),  Ensembl(GRCz11):ENSDARG00000074431 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027979Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • m863 Point Mutation Donor Splice Site Cryptic Donor Splice Site, Frameshift ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ddb1 N/A 1
    MO2-ddb1 N/A 1
    DISEASE ASSOCIATED WITH ddb1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ddb1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of apoptotic process (more)
    Cellular Component nucleus (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ddb1-001 (1) 1845
    ddb1-201 (1)    Ensembl 1659
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ddb1 No data available
    MARKER RELATIONSHIPS
    ddb1 Encodes: [cDNA] MGC:63840 (1), MGC:174005 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200626 (1) 3686 nt
    Polypeptide UniProtKB:A0A0G2KCW6 (1) 1142 aa
    Sequence Information (all 17)
    ORTHOLOGY for ddb1 ( Chr: 18 )
    CITATIONS (22)