ZFIN ID: ZDB-GENE-040426-1271
Gene Name: protein phosphatase 1, regulatory subunit 8b
Gene Symbol: ppp1r8b    Nomenclature History

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Previous Name: zgc:63827

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have mRNA binding activity and protein serine/threonine phosphatase inhibitor activity. Predicted to be involved in negative regulation of protein dephosphorylation and production of miRNAs involved in gene silencing by miRNA. Predicted to localize to the nuclear speck. Orthologous to human PPP1R8 (protein phosphatase 1 regulatory subunit 8).
Genome Resources: Alliance (1),  Gene:799896 (1),  Ensembl(GRCz11):ENSDARG00000022430 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH ppp1r8b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH ppp1r8b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component nuclear speck (more)
Molecular Function mRNA binding (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000253 Forkhead-associated (FHA) domain
Homologous_superfamily IPR008984 SMAD/FHA domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ppp1r8b-201 (1)    Ensembl 4915
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ppp1r8b No data available
MARKER RELATIONSHIPS
ppp1r8b Contained in: [BAC] CH211-256M12 (1)
ppp1r8b Encodes: [cDNA] MGC:63827 (1)
ppp1r8b Has Artifact: [EST] fb68h07
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_201200 (1) 2590 bp
Genomic GenBank:BX927222 (1) 154714 bp
Select Tool
Polypeptide UniProtKB:F1RDJ3 (1) 349 aa
Sequence Information (all 9)
ORTHOLOGY for ppp1r8b ( Chr: 16 )
CITATIONS (13)