ZFIN ID: ZDB-GENE-040426-1262
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Gene Name: |
aldehyde dehydrogenase 2 family member, tandem duplicate 1
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Gene Symbol: |
aldh2.1
Nomenclature History
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Previous Names:
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aldh2 (1),
aldh2a,
zgc:63786
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Attributions for Alias: {{control.newAlias}}
Delete Alias:
(Including Attributions)
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Gene Type: |
protein_coding_gene
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Location: |
Chr:
5
Mapping Details/Browsers
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Description: |
Exhibits 3-chloroallyl aldehyde dehydrogenase activity. Predicted to be involved in cellular aldehyde metabolic process. Human ortholog(s) of this gene implicated in several diseases, including alcohol use disorder; artery disease (multiple); diabetes mellitus (multiple); diabetic neuropathy; and liver disease (multiple). Is expressed in several structures, including fin; heart; liver; musculature system; and pleuroperitoneal region. Orthologous to human ALDH2 (aldehyde dehydrogenase 2 family member).
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Genome Resources:
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Alliance
(1),
Gene:393462
(1),
Ensembl(GRCz11):ENSDARG00000089924
(2)
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MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent |
Created Alleles |
Publications |
MO1-aldh2.1 |
N/A
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1
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PHENOTYPE
No data available
DISEASE ASSOCIATED WITH aldh2.1 HUMAN ORTHOLOG
Disease Ontology Term |
Multi-Species Data |
OMIM Term |
OMIM Phenotype ID |
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Alcohol sensitivity, acute |
610251 |
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{Esophageal cancer, alcohol-related, susceptibility to} |
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{Hangover, susceptibility to} |
610251 |
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{Sublingual nitroglycerin, susceptibility to poor response to} |
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DISEASE ASSOCIATED WITH aldh2.1 VIA EXPERIMENTAL MODELS
No data available
TRANSCRIPTS
Type |
Name |
Length (nt) |
Analysis
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|
mRNA
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aldh2.1-201
(1)
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1935
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INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM aldh2.1
No data available
ORTHOLOGY for aldh2.1 (
Chr:
5
)