ZFIN Gene: aldh2.1

ZFIN ID: ZDB-GENE-040426-1262

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Gene Name:	aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1
Gene Symbol:	aldh2.1
Previous Names:	aldh2 (1), aldh2a, zgc:63786
Location:	Chr: 5 Mapping Details/Browsers
Nomenclature History

Gene Name:

aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1

Gene Symbol:

aldh2.1

Previous Names:

aldh2 (1), aldh2a, zgc:63786

Location:

Chr: 5 Mapping Details/Browsers

Nomenclature History

GENE EXPRESSION
All Expression Data:	2 figures from 2 publications
Wild-type Stages, Structures:	Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
	brain , caudal fin , eye , gill (all 13)
Curated Microarray Expression:	GEO (1)

GENE EXPRESSION

All Expression Data:

2 figures from 2 publications

Wild-type Stages, Structures:

Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)

brain, caudal fin, eye, gill (all 13) expand

Curated Microarray Expression:

GEO (1)

DISEASE ASSOCIATED WITH aldh2.1 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
	{Esophageal cancer, alcohol-related, susceptibility to}
	Alcohol sensitivity, acute	610251
	{Hangover, susceptibility to}	610251
	{Sublingual nitroglycerin, susceptibility to poor response to}

Ontology	GO Term
Biological Process	cellular aldehyde metabolic process (more)
Cellular Component	cellular_component (more)
Molecular Function	3-chloroallyl aldehyde dehydrogenase activity (more)

Ontology

GO Term

Biological Process

cellular aldehyde metabolic process (more)

Cellular Component

cellular_component (more)

Molecular Function

3-chloroallyl aldehyde dehydrogenase activity (more)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR015590 (1) InterPro:IPR016160 (1) InterPro:IPR016161 (1) InterPro:IPR016162 (1) InterPro:IPR016163 (1) InterPro:IPR029510 (1)	PROSITE:PS00070 (1) PROSITE:PS00687 (1)	Pfam:PF00171 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	aldh2.1-001 (1)	1935	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

aldh2.1Contained in:	[BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1) (order this)
aldh2.1Encodes:	[cDNA] MGC:63786 (1) (order this)

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_200490 (1)	1940bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CT978957 (1)	164556bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A0R4IUZ2 (1)	516aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:28434 (1)

Type

Accession #

Length (bp/aa)

Analysis

RNA

RefSeq:NM_200490 (1)

1940bp

Select Tool

ZFIN BLAST

NCBI BLAST

Ensembl

UCSC BLAT

Vega

Genomic

GenBank:CT978957 (1)

164556bp

Select Tool

MegaBLAST

Ensembl

Polypeptide

UniProtKB:A0A0R4IUZ2 (1)

516aa

Select Tool

ZFIN BLAST

SIB BLAST

Ensembl Protein Blast

Vega Protein Blast

Sequence Clusters

UniGene:28434 (1)

ORTHOLOGY for aldh2.1 (Chr: 5)

Species	Symbol	Chromosome	Accession #	Evidence
Human	ALDH2	12	Gene:217 OMIM:100650 HGNC:404	Amino acid sequence comparison (5) Conserved genome location (synteny) (1)
Mouse	Aldh2	5	MGI:99600 Gene:11669	Amino acid sequence comparison (3)

Download Curated Orthology