ZFIN ID: ZDB-GENE-040426-1262
Gene Name: aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1
Gene Symbol: aldh2.1
Previous Names: aldh2 (1), aldh2a, zgc:63786
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
  brain, caudal fin, eye, gill (all 13) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Targeting reagents: MO1-aldh2.1 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH aldh2.1 HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
Alcohol sensitivity, acute 610251
{Esophageal cancer, alcohol-related, susceptibility to}
{Sublingual nitroglycerin, susceptibility to poor response to}
{Hangover, susceptibility to} 610251
GENE ONTOLOGY 
Ontology GO Term
Biological Process cellular aldehyde metabolic process (more)
Cellular Component cellular_component (more)
Molecular Function 3-chloroallyl aldehyde dehydrogenase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR015590 (1)
  • InterPro:IPR016160 (1)
  • InterPro:IPR016161 (1)
  • InterPro:IPR016162 (1)
  • InterPro:IPR016163 (1)
  • InterPro:IPR029510 (1)
  • PROSITE:PS00070 (1)
  • PROSITE:PS00687 (1)
  • Pfam:PF00171 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA aldh2.1-001 (1) 1935
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aldh2.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    aldh2.1Contained in: [BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1) (order this)
    aldh2.1Encodes: [cDNA] MGC:63786 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200490 (1) 1940bp
    Genomic GenBank:CT978957 (1) 164556bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IUZ2 (1) 516aa
    Sequence Clusters UniGene:28434 (1)
    Sequence Information (all 14)
    OTHER aldh2.1 GENE PAGES 
  • Gene:393462 (1)
  • VEGA:OTTDARG00000018931 (1)
  • Ensembl(GRCz10):ENSDARG00000089924 (1)
  • ORTHOLOGY for aldh2.1 (Chr: 5) 
    Species Symbol Chromosome Accession # Evidence
    Human ALDH2 12
  • Gene:217
  • OMIM:100650
  • HGNC:404
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (1)
    Mouse Aldh2 5
  • MGI:99600
  • Gene:11669
  • Amino acid sequence comparison (3)
    Download Curated Orthology
    CITATIONS (26)