ZFIN Gene: aldh2.1

ZFIN ID: ZDB-GENE-040426-1262

ZFIN ID: ZDB-GENE-040426-1262

Gene Name:	aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1
Gene Symbol:	aldh2.1
Previous Names:	aldh2 (1), aldh2a, zgc:63786
Location:	Chr: 5 Details
Nomenclature History

GENE EXPRESSION
All Expression Data:	2 figures from 2 publications
Wild-type Stages, Structures:	Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
	brain , caudal fin , eye , gill (all 13)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

Knockdown reagents:

MO1-aldh2.1 (1)

PHENOTYPE

Phenotype of Human Orthologue	OMIM Phenotype ID
Alcohol sensitivity, acute	610251
{Esophageal cancer, alcohol-related, susceptibility to}
{Hangover, susceptibility to}	610251
{Sublingual nitroglycerin, susceptibility to poor response to}

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cellular aldehyde metabolic process (more)
Cellular Component	cellular_component (more)
Molecular Function	3-chloroallyl aldehyde dehydrogenase activity (more)

GO Terms (all 7)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR015590 (1) InterPro:IPR016160 (1) InterPro:IPR016161 (1) InterPro:IPR016162 (1) InterPro:IPR016163 (1) InterPro:IPR029510 (1)	PROSITE:PS00070 (1) PROSITE:PS00687 (1)	Pfam:PF00171 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	aldh2.1-001 (1)	1935	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM aldh2.1 No data available

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

aldh2.1 Contained in:	[BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1) (order this)
aldh2.1 Encodes:	[cDNA] MGC:63786 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_200490 (1)	1940 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CT978957 (1)	164556 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A2BGR9 (1)	516 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:28434 (1)

OTHER aldh2.1 GENE PAGES

Gene:393462 (1)

VEGA:OTTDARG00000018931 (1)

Ensembl(Zv9):ENSDARG00000089924 (1)

ORTHOLOGY

CITATIONS (24)