ZFIN ID: ZDB-GENE-040426-1262
Gene Name: aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1
Gene Symbol: aldh2.1
Previous Names: aldh2 (1), aldh2a, zgc:63786
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
  brain, caudal fin, eye, gill (all 13) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-aldh2.1 (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH aldh2.1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
{Esophageal cancer, alcohol-related, susceptibility to}
Alcohol sensitivity, acute 610251
{Hangover, susceptibility to} 610251
{Sublingual nitroglycerin, susceptibility to poor response to}
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular aldehyde metabolic process (more)
Cellular Component cellular_component (more)
Molecular Function 3-chloroallyl aldehyde dehydrogenase activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR015590 (1)
  • InterPro:IPR016160 (1)
  • InterPro:IPR016161 (1)
  • InterPro:IPR016162 (1)
  • InterPro:IPR016163 (1)
  • InterPro:IPR029510 (1)
  • PROSITE:PS00070 (1)
  • PROSITE:PS00687 (1)
  • Pfam:PF00171 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA aldh2.1-001 (1) 1935
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM aldh2.1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    aldh2.1Contained in: [BAC] CH211-157P22 (1) (order this), DKEY-204G14 (1) (order this)
    aldh2.1Encodes: [cDNA] MGC:63786 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200490 (1) 1940bp
    Genomic GenBank:CT978957 (1) 164556bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IUZ2 (1) 516aa
    Sequence Clusters UniGene:28434 (1)
    Sequence Information (all 14)
    OTHER aldh2.1 GENE PAGES
  • Gene:393462 (1)
  • VEGA:OTTDARG00000018931 (1)
  • Ensembl(GRCz10):ENSDARG00000089924 (1)
  • ORTHOLOGY for aldh2.1 (Chr: 5)
    Species Symbol Chromosome Accession # Evidence
    Human ALDH2 12
  • Gene:217
  • OMIM:100650
  • HGNC:404
  • Amino acid sequence comparison (5)
    Conserved genome location (synteny) (1)
    Mouse Aldh2 5
  • MGI:99600
  • Gene:11669
  • Amino acid sequence comparison (3)
    Download Curated Orthology
    CITATIONS (26)