ZFIN ID: ZDB-GENE-040426-1227
Gene Name: leucine rich repeat and fibronectin type III domain containing 1
Gene Symbol: lrfn1    Nomenclature History

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Previous Names: mb21d2b, zgc:63670

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to localize to cell surface and integral component of postsynaptic density membrane. Is expressed in brain and neurons. Orthologous to human LRFN1 (leucine rich repeat and fibronectin type III domain containing 1).
Genome Resources: Alliance (1),  Gene:393587 (1),  Ensembl(GRCz11):ENSDARG00000027602 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [MGC:63670]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8956 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10889 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42629 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lrfn1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lrfn1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component cell junction (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lrfn1-201 (1)    Ensembl 1857
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lrfn1 No data available
    MARKER RELATIONSHIPS
    lrfn1 Contained in: [Fosmid] CH1073-98B19 (1), CH1073-318N3 (1)
    lrfn1 Encodes: [cDNA] MGC:63670 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200615 (1) 2101 nt
    Genomic GenBank:CU499339 (1) 35341 nt
    Select Tool
    Polypeptide UniProtKB:E7EZ70 (1) 584 aa
    Sequence Information (all 29)
    ORTHOLOGY for lrfn1 ( Chr: 15 )
    CITATIONS (18)