ZFIN ID: ZDB-GENE-040426-1216
Gene Name: phosphatidylinositol glycan anchor biosynthesis, class B
Gene Symbol: pigb    Nomenclature History

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Previous Name: zgc:63658 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to localize to endoplasmic reticulum and endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B).
Genome Resources: Alliance (1),  Gene:393448 (1),  Ensembl(GRCz11):ENSDARG00000105011 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63658]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa30387 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pigb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Epileptic encephalopathy, early infantile, 80 618580
DISEASE ASSOCIATED WITH pigb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process GPI anchor biosynthetic process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function mannosyltransferase activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pigb No data available
MARKER RELATIONSHIPS
pigb Encodes: [cDNA] MGC:63658 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200476 (1)
Genomic GenBank:CABZ01069901 (1) 10807 nt
Polypeptide UniProtKB:A0A0R4IFP6 (1) 536 aa
Sequence Information (all 11)
ORTHOLOGY for pigb ( Chr: 18 )
CITATIONS (20)