Gene

xpa

ID
ZDB-GENE-040426-1205
Name
xeroderma pigmentosum, complementation group A
Symbol
xpa Nomenclature History
Previous Names
  • zgc:63640
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable damaged DNA binding activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within nucleotide-excision repair. Predicted to be located in nucleus. Predicted to be part of nucleotide-excision repair factor 1 complex. Is expressed in liver and telencephalon. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group A. Orthologous to human XPA (XPA, DNA damage recognition and repair factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xpa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
xeroderma pigmentosum group A Alliance Xeroderma pigmentosum, group A 278700
Associated With xpa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR022652 Zinc finger, XPA-type, conserved site
Domain IPR022656 XPA, C-terminal
Domain IPR027838 Domain of unknown function DUF4585
Family IPR000465 XPA
Homologous_superfamily IPR009061 Putative DNA-binding domain superfamily
Homologous_superfamily IPR037129 XPA domain superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF4585 Putative DNA-binding domain superfamily XPA XPA, C-terminal XPA domain superfamily Zinc finger, XPA-type, conserved site
UniProtKB:A0A8M3AY35 277
UniProtKB:Q7SY02 549
UniProtKB:A0A8M3BDZ6 276
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations