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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1184
Gene Name: cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2
Gene Symbol: cyp46a1.2
Sequence Ontology ID : SO:0001217

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Previous Names: cyp46a2, zgc:63602

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cholesterol 24-hydroxylase activity; heme binding activity; and iron ion binding activity. Predicted to be involved in cholesterol catabolic process and oxidation-reduction process.  ...
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (1 image) from Thisse et al., 2004 [MGC:63602]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa29302 Point Mutation Unknown Splice Site ENU
sa43377 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cyp46a1.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cyp46a1.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cholesterol catabolic process (more)
    Molecular Function cholesterol 24-hydroxylase activity (more)
    GO Terms (all 6)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp46a1.2 No data available
    MARKER RELATIONSHIPS
    cyp46a1.2 Encodes: [cDNA] MGC:63602 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200461 (1) 1851 bp
    Genomic GenBank:CABZ01045952 (1) 9916 bp
    Polypeptide UniProtKB:F1Q9I2 (1) 444 aa
    Sequence Clusters UniGene:84970 (1)
    Sequence Information (all 14)
    OTHER cyp46a1.2 GENE PAGES
  • Alliance (1)
  • Gene:393433 (1)
  • Ensembl(GRCz11):ENSDARG00000004262 (2)
  • ORTHOLOGY for cyp46a1.2 ( Chr: 20 )
    CITATIONS (15)