ZFIN ID: ZDB-GENE-040426-1181
Gene Name: forkhead box L1
Gene Symbol: foxl1    Nomenclature History

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Previous Name: zgc:63595

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Exhibits DNA-binding transcription factor activity. Involved in animal organ development; negative regulation of transcription, DNA-templated; and pectoral fin morphogenesis. Predicted to localize to nucleus. Is expressed in several structures, including brain; digestive system; head; pleuroperitoneal region; and presumptive neural retina. Orthologous to human FOXL1 (forkhead box L1).
Genome Resources: Alliance (1),  Gene:393959 (1),  Ensembl(GRCz11):ENSDARG00000008133 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1842 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-foxl1 N/A 1
    MO2-foxl1 N/A 1
    DISEASE ASSOCIATED WITH foxl1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH foxl1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function DNA-binding transcription factor activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA foxl1-201 (1)    Ensembl 1863
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM foxl1 No data available
    MARKER RELATIONSHIPS
    foxl1 Contained in: [BAC] DKEY-102F14 (1) (order this)
    foxl1 Encodes: [cDNA] MGC:63595 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200984 (1) 1889 nt
    Genomic GenBank:BX908765 (1) 155120 nt
    Select Tool
    Polypeptide UniProtKB:Q7SY22 (1) 363 aa
    Sequence Information (all 11)
    ORTHOLOGY for foxl1 ( Chr: 18 )
    CITATIONS (28)