ZFIN ID: ZDB-GENE-040426-1180
Gene Name: nucleoporin 98 and 96 precursor
Gene Symbol: nup98    Nomenclature History

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Previous Names: im:7151238, zgc:63593

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and nuclear localization sequence binding activity. Involved in enteric nervous system development. Predicted to localize to the nuclear pore cytoplasmic filaments. Human ortholog(s) of this gene implicated in precursor T-lymphoblastic lymphoma/leukemia. Is expressed in central nervous system and intestine. Orthologous to human NUP98 (nucleoporin 98).
Genome Resources: Alliance (1),  Gene:777756 (1),  Ensembl(GRCz11):ENSDARG00000074955 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7151238]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17239 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29656 Point Mutation Unknown Premature Stop ENU
    sa37372 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-nup98
    1
    MO1-nup98 N/A 1
    MO2-nup98 N/A 1
    MO3-nup98 N/A 1
    MO4-nup98 N/A 1
    PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH nup98 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nup98 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process enteric nervous system development (more)
    Cellular Component nuclear pore (more)
    Molecular Function structural constituent of nuclear pore (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR007230 Peptidase S59, nucleoporin
    Domain IPR021967 Nuclear protein 96
    Family IPR037637 Nuclear pore complex protein NUP98-NUP96
    Family IPR037665 Nucleoporin peptidase S59-like
    Homologous_superfamily IPR036903 Peptidase S59, nucleoporin superfamily
    Repeat IPR025574 Nucleoporin FG repeat
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nup98-203 (1)    Ensembl 6756
    ncRNA nup98-003 (1)    Ensembl 912
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nup98 No data available
    MARKER RELATIONSHIPS
    nup98 Contained in: [BAC] DKEY-36I3 (1) (order this)
    nup98 Encodes: [EST] IMAGE:7151238 (1)
    [cDNA] MGC:63593 (1)
    nup98 Has Artifact: [cDNA] MGC:113968 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077797 (1) 1893 nt
    Genomic GenBank:CR847523 (1) 148002 nt
    Select Tool
    Polypeptide UniProtKB:E7F981 (1) 1814 aa
    Sequence Information (all 20)
    ORTHOLOGY for nup98 ( Chr: 21 )
    CITATIONS (19)