ZFIN ID: ZDB-GENE-040426-1152
Gene Name: argininosuccinate lyase
Gene Symbol: asl
Previous Name: zgc:63532 (1)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 3 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:63532]
Wild-type Stages, Structures: Cleavage:32-cell (1.75h-2.0h) to Adult (90d-730d, breeding adult)
  ball, brain anterior region, lens, liver (all 8) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa12812 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa13022 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH asl HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    argininosuccinic aciduria Argininosuccinic aciduria 207900
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process arginine biosynthetic process via ornithine (more)
    Cellular Component cytosol (more)
    Molecular Function argininosuccinate lyase activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000362 (1)
  • InterPro:IPR008948 (1)
  • InterPro:IPR009049 (1)
  • InterPro:IPR020557 (1)
  • InterPro:IPR022761 (1)
  • InterPro:IPR024083 (1)
  • InterPro:IPR029419 (1)
  • PROSITE:PS00163 (1)
  • Pfam:PF00206 (1)
  • Pfam:PF14698 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA asl-001 (1) 1811
    asl-002 (1) 835
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM asl No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    aslContained in: [BAC] DKEY-225F3 (1) (order this)
    aslEncodes: [cDNA] MGC:63532 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200451 (1) 1809bp
    Genomic GenBank:CR450753 (1) 160631bp
    Select Tool
    Polypeptide UniProtKB:F1RA91 (1) 465aa
    Sequence Clusters UniGene:133031 (1)
    Sequence Information (all 12)
    OTHER asl GENE PAGES 
  • Gene:393423 (1)
  • VEGA:OTTDARG00000022678 (1)
  • Ensembl(GRCz10):ENSDARG00000033361 (1)
  • ORTHOLOGY for asl (Chr: 21) 
    Species Symbol Chromosome Accession # Evidence
    Human ASL 7
  • Gene:435
  • OMIM:608310
  • HGNC:746
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Asl 5
  • MGI:88084
  • Gene:109900
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (19)