ZFIN ID: ZDB-GENE-040426-1152
Gene Name: argininosuccinate lyase
Gene Symbol: asl
Previous Name: zgc:63532 (1)
Location: Chr: 21   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [MGC:63532]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  ball, brain anterior region, lens, liver (all 8) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa12812, sa13022
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Argininosuccinic aciduria 207900
GENE ONTOLOGY
Ontology GO Term
Biological Process arginine biosynthetic process via ornithine (more)
Molecular Function argininosuccinate lyase activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000362 (1)
  • InterPro:IPR008948 (1)
  • InterPro:IPR009049 (1)
  • InterPro:IPR020557 (1)
  • InterPro:IPR022761 (1)
  • InterPro:IPR024083 (1)
  • InterPro:IPR029419 (1)
  • PROSITE:PS00163 (1)
  • Pfam:PF00206 (1)
  • Pfam:PF14698 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA asl-001 (1) 1811
    asl-002 (1) 835
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM asl No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    asl Contained in: [BAC] DKEY-225F3 (1)
    asl Encodes: [cDNA] MGC:63532 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200451 (1) 1809 bp
    Genomic GenBank:CR450753 (1) 160631 bp
    Select Tool
    Polypeptide UniProtKB:F1RA91 (1) 465 aa
    Sequence Clusters UniGene:133031 (1)
    Sequence Information (all 12)
    OTHER asl GENE PAGES
  • Gene:393423 (1)
  • VEGA:OTTDARG00000022678 (1)
  • Ensembl(Zv9):ENSDARG00000033361 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish asl 21  
    Human ASL 7 (7q11.21)
  • OMIM:608310
  • Gene:435
  • Mouse Asl 5 ( 68.37 cM)
  • MGI:88084
  • Gene:109900
  • Orthology Details
    CITATIONS (17)