Gene

dnajb6b

ID
ZDB-GENE-040426-1122
Name
DnaJ heat shock protein family (Hsp40) member B6b
Symbol
dnajb6b Nomenclature History
Previous Names
  • dnajb6
  • zgc:56709 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Involved in several processes, including myofibril assembly; negative regulation of response to endoplasmic reticulum stress; and skeletal muscle organ development. Localizes to nuclear envelope. Is expressed in Purkinje cell; heart; lens; and solid lens vesicle. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 1 and distal spinal muscular atrophy type 5. Orthologous to several human genes including DNAJB6 (DnaJ heat shock protein family (Hsp40) member B6).
Genome Resources
Note
None
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dnajb6b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant limb-girdle muscular dystrophy type 1 Alliance Muscular dystrophy, limb-girdle, autosomal dominant 1 603511
Associated With dnajb6b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018253 DnaJ domain, conserved site
Domain IPR001623 DnaJ domain
Homologous_superfamily IPR036869 Chaperone J-domain superfamily
Domain Details Per Protein
Protein Length Chaperone J-domain superfamily DnaJ domain DnaJ domain, conserved site
UniProtKB:Q1LY18 237
UniProtKB:A0A2R8QPK4 229
UniProtKB:A0A1D5NSC8 311
UniProtKB:Q7ZW83 237
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations