Gene

cwc27

ID

ZDB-GENE-040426-1118

Name

CWC27 spliceosome associated cyclophilin

Symbol

cwc27 Nomenclature History

Previous Names

zgc:56702 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to act upstream of or within protein peptidyl-prolyl isomerization. Predicted to be located in nucleus. Predicted to be part of U2-type precatalytic spliceosome and catalytic step 2 spliceosome. Orthologous to human CWC27 (CWC27 spliceosome associated cyclophilin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cwc27 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Retinitis pigmentosa with or without skeletal anomalies	250410

Associated With cwc27 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020892	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain	IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Family	IPR044666	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like
Homologous_superfamily	IPR029000	Cyclophilin-like domain superfamily