ZFIN ID: ZDB-GENE-040426-1097
Gene Name: macoilin 1a
Gene Symbol: maco1a    Nomenclature History

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Previous Names: tmem57, tmem57a, zgc:56620 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity and microtubule binding activity. Predicted to be involved in chemotaxis and neuronal signal transduction. Predicted to localize to nuclear membrane and rough endoplasmic reticulum membrane. Orthologous to human MACO1 (macoilin 1).
Genome Resources: Alliance (1),  Gene:393289 (1),  Ensembl(GRCz11):ENSDARG00000005625 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56620]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1411 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23542 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36859 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH maco1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH maco1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuronal signal transduction (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA maco1a-201 (1)    Ensembl 2577
    ncRNA tmem57a-002 (1)    Ensembl 445
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM maco1a No data available
    MARKER RELATIONSHIPS
    maco1a Contained in: [BAC] CH211-150A9 (1), DKEY-264P5 (1) (order this)
    maco1a Encodes: [EST] fc41h01 (1)
    [cDNA] MGC:56620 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200319 (1) 2001 nt
    Genomic GenBank:CU469458 (1) 131134 nt
    Select Tool
    Polypeptide UniProtKB:Q2TLY2 (1) 664 aa
    Sequence Information (all 16)
    ORTHOLOGY for maco1a ( Chr: 19 )
    CITATIONS (25)