ppil2

ID

ZDB-GENE-040426-1096

Name

peptidylprolyl isomerase (cyclophilin)-like 2

Symbol

ppil2 Nomenclature History

Previous Names

si:dkeyp-86g2.1
zgc:56616
zgc:86735

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein folding. Predicted to act upstream of or within protein peptidyl-prolyl isomerization and protein ubiquitination. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PPIL2 (peptidylprolyl isomerase like 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56616 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ppil2 Human Ortholog

No data available

Associated With ppil2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020892	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain	IPR002130	Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Domain	IPR003613	U-box domain
Domain	IPR026951	Peptidyl-prolyl cis-trans isomerase like 2, U-box domain
Family	IPR044666	Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR029000	Cyclophilin-like domain superfamily