Gene

mad1l1

ID
ZDB-GENE-040426-1081
Name
mitotic arrest deficient 1 like 1
Symbol
mad1l1 Nomenclature History
Previous Names
  • zgc:56571 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore and mitotic spindle assembly checkpoint. Predicted to localize to kinetochore; mitotic spindle; and nuclear envelope. Human ortholog(s) of this gene implicated in lymphoma and prostate cancer. Orthologous to human MAD1L1 (mitotic arrest deficient 1 like 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mad1l1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
prostate cancer Alliance Prostate cancer, somatic 176807
Lymphoma, somatic
Associated With mad1l1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008672 Spindle assembly checkpoint component Mad1
Domain Details Per Protein
Protein Length Spindle assembly checkpoint component Mad1
UniProtKB:Q7ZW71 323
UniProtKB:D9IWE2 717
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations