Gene
ptgesl
- ID
- ZDB-GENE-040426-1063
- Name
- prostaglandin E synthase 2-like
- Symbol
- ptgesl Nomenclature History
- Previous Names
-
- zgc:56527 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have several functions, including glutathione binding activity; heme binding activity; and prostaglandin-E synthase activity. Predicted to be involved in cell redox homeostasis and prostaglandin biosynthetic process. Predicted to localize to Golgi membrane and mitochondrion. Is expressed in female organism; male organism; and reproductive system. Orthologous to human PTGES2 (prostaglandin E synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7140538 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR011767 | Glutaredoxin active site |
Domain | IPR004045 | Glutathione S-transferase, N-terminal |
Domain | IPR004046 | Glutathione S-transferase, C-terminal |
Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
Domain | IPR034335 | Prostaglandin E synthase 2, C-terminal |
Family | IPR034334 | Prostaglandin E synthase 2 |
Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
Protein | Length | Glutaredoxin active site | Glutathione S-transferase, C-terminal | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione S-transferase, N-terminal | Prostaglandin E synthase 2 | Prostaglandin E synthase 2, C-terminal | Thioredoxin-like superfamily |
---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QDX0
|
237 | ||||||||
UniProtKB:A0A8M9PR36
|
233 | ||||||||
UniProtKB:Q7ZUC7
|
377 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
ptgesl-201
(1)
|
Havana | 1989 nt | |
mRNA |
ptgesl-204
(1)
|
Ensembl | 1475 nt | |
ncRNA |
ptgesl-002
(1)
|
Havana | 722 nt | |
ncRNA |
ptgesl-003
(1)
|
Havana | 728 nt |
Interactions and Pathways
No data available
Plasmids
No data available