ZFIN ID: ZDB-GENE-040426-1007
Gene Name: isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha
Gene Symbol: idh3a    Nomenclature History

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Previous Names: zgc:56380 (1), zgc:85631

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to localize to mitochondrion. Is expressed in several structures, including alar plate midbrain region; mesoderm; musculature system; optic tectum; and pronephric duct. Orthologous to human IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha).
Genome Resources: Alliance (1),  Gene:393926 (1),  Ensembl(GRCz11):ENSDARG00000030278 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023252Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38087 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH idh3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH idh3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function isocitrate dehydrogenase (NAD+) activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA idh3a-202 (1)    Ensembl 1438
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM idh3a No data available
    MARKER RELATIONSHIPS
    idh3a Contained in: [BAC] DKEY-200J6 (1) (order this)
    idh3a Encodes: [EST] fc54c04 (1)
    [cDNA] MGC:56380 (1), MGC:85631 (1), MGC:173889 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200951 (1) 1395 nt
    Genomic GenBank:CR381664 (1) 277093 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NV33 (1) 365 aa
    Sequence Information (all 22)
    ORTHOLOGY for idh3a ( Chr: 25 )
    CITATIONS (32)