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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1006
Gene Name: sigma non-opioid intracellular receptor 1
Gene Symbol: sigmar1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: oprs1, zgc:56378 (1)

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(Including Attributions)
Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in response to wounding. Predicted to localize to the endoplasmic reticulum and integral component of membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis  ...
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56378]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
f19 Insertion Unknown Frameshift CRISPR
f20 Indel Unknown Frameshift CRISPR
Targeting reagents:
PHENOTYPE
Data: Fig. S20 from Rennekamp et al., 2016
Observed in:
DISEASE ASSOCIATED WITH sigmar1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
amyotrophic lateral sclerosis type 16 ?Amyotrophic lateral sclerosis 16, juvenile 614373
distal spinal muscular atrophy 2 ?Spinal muscular atrophy, distal, autosomal recessive, 2 605726
DISEASE ASSOCIATED WITH sigmar1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to wounding (more)
Cellular Component integral component of membrane (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006716 (1)
  • Pfam:PF04622 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA sigmar1-201 (1) 1154
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM sigmar1 No data available
    MARKER RELATIONSHIPS
    sigmar1Contained in: [BAC] CH211-262G12 (1) (order this)
    sigmar1Encodes: [cDNA] MGC:56378 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200977 (1) 1175bp
    Genomic GenBank:BX927402 (1) 155963bp
    Select Tool
    Polypeptide UniProtKB:F1QUF7 (1) 222aa
    Sequence Clusters UniGene:84840 (1)
    Sequence Information (all 13)
    ORTHOLOGY for sigmar1 (Chr: 10)
    CITATIONS (26)