ZFIN ID: ZDB-GENE-040426-1002
Gene Name: hydroxysteroid (11-beta) dehydrogenase 1-like a
Gene Symbol: hsd11b1la    Nomenclature History

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Previous Names: hsd11b3, hsd11b3a, sdr10b (1), zgc:56373 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have steroid dehydrogenase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to the extracellular region. Is expressed in intestinal bulb. Orthologous to human HSD11B1L (hydroxysteroid 11-beta dehydrogenase 1 like).
Genome Resources: Alliance (1),  Gene:393293 (1),  Ensembl(GRCz11):ENSDARG00000071377 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (2 images) from Thisse et al., 2004 [MGC:56373]
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10947 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hsd11b1la HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hsd11b1la VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component extracellular region (more)
    Molecular Function steroid dehydrogenase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR002347 Short-chain dehydrogenase/reductase SDR
    Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
    Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hsd11b1la-201 (1)    Ensembl 1501
    hsd11b1la-202 (1)    Ensembl 1504
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hsd11b1la No data available
    MARKER RELATIONSHIPS
    hsd11b1la Contained in: [BAC] DKEY-78L4 (1) (order this), DKEYP-93A3 (1)
    hsd11b1la Encodes: [cDNA] MGC:56373 (1), MGC:86784 (1), MGC:174399 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200323 (1) 1519 bp
    Genomic GenBank:BX936298 (1) 234949 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q6PUF3 (1) 287 aa
    Sequence Information (all 19)
    ORTHOLOGY for hsd11b1la ( Chr: 22 )
    CITATIONS (34)