ZFIN ID: ZDB-GENE-040415-2
Gene Name: motor neuron and pancreas homeobox 2b
Gene Symbol: mnx2b    Nomenclature History

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Attributions

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Previous Names: mnr2b (1), hlxb9lb (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity. Involved in spinal cord motor neuron cell fate specification. Predicted to localize to nucleus. Is expressed in several structures, including endodermal cell; lateral mesoderm; motor neurons; spinal cord; and spinal cord neural tube.
Genome Resources: Alliance (1),  Gene:406206 (1),  Ensembl(GRCz11):ENSDARG00000030350 (1)
Note: The name of this gene was changed from hlxb9lb to mnx2b to more accurately reflect its relationship to the MNX family of genes.
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-mnx2b N/A 4
MO2-mnx2b N/A 1
MO3-mnx2b N/A 1
MO4-mnx2b N/A 1
PHENOTYPE
Data: Fig. S5 from See et al., 2014
Observed in:
DISEASE ASSOCIATED WITH mnx2b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH mnx2b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process spinal cord motor neuron cell fate specification (more)
Cellular Component nucleus (more)
Molecular Function DNA-binding transcription factor activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mnx2b-201 (1)    Ensembl 1031
mnx2b-202 (1)    Ensembl 1152
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mnx2b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
TgBAC(mnx2b-hsp70l:GAL4FF) hsp70lmnx2b GAL4FF Danio rerio 1 1
TgBAC(mnx2b:GAL4FF) mnx2b GAL4FF Danio rerio 1 9
MARKER RELATIONSHIPS
mnx2b Contained in: [BAC] CH211-172N16 (1)
mnx2b Encodes: [cDNA] MGC:194669 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001009887 (1) 1032 nt
Genomic GenBank:CR762428 (1) 140219 nt
Select Tool
Polypeptide UniProtKB:B3DJ06 (1) 328 aa
Sequence Information (all 15)
ORTHOLOGY for mnx2b ( Chr: 1 )
CITATIONS (27)