Gene

eif4ea

ID
ZDB-GENE-040413-1
Name
eukaryotic translation initiation factor 4ea
Symbol
eif4ea Nomenclature History
Previous Names
  • eif4E-1A (1)
  • eif4e1a
  • eif4e
  • zgc:86680
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Exhibits RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Involved in translational initiation. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Robalino et al., 2004
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif4ea Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
{Autism, susceptibility to, 19} 615091
Associated With eif4ea Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019770 Eukaryotic translation initiation factor 4E (eIF-4E), conserved site
Family IPR001040 Translation Initiation factor eIF- 4e
Homologous_superfamily IPR023398 Translation Initiation factor eIF- 4e-like
Domain Details Per Protein
Protein Length Eukaryotic translation initiation factor 4E (eIF-4E), conserved site Translation Initiation factor eIF- 4e Translation Initiation factor eIF- 4e-like
UniProtKB:Q9DFS6 215
UniProtKB:F1Q900 215
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations