ZFIN ID: ZDB-GENE-040406-2
Gene Name: gap junction protein, alpha 2
Gene Symbol: gja2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: cx39.9 (1), cx46l (1), zgc:110668

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have gap junction channel activity. Involved in cell communication by electrical coupling and slow-twitch skeletal muscle fiber contraction. Predicted to localize to connexin complex. Is expressed in several structures, including eye; kidney; liver; musculature system; and spinal cord.
Genome Resources: Alliance (1),  Gene:404726 (1),  Ensembl(GRCz11):ENSDARG00000004082 (1)
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2005 [eu255]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
mi264 Point Mutation Unknown Missense ENU
sa11137 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cx39.9 N/A 1
    DISEASE ASSOCIATED WITH gja2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gja2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell communication by electrical coupling (more)
    Cellular Component cell junction (more)
    Molecular Function gap junction channel activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cx39.9-201 (1)    Ensembl 1239
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gja2 No data available
    MARKER RELATIONSHIPS
    gja2 Contained in: [BAC] DKEY-110K5 (order this)
    gja2 Encodes: [EST] eu255 (1)
    [cDNA] MGC:110668 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212826 (1) 1062 nt
    Genomic GenBank:AL929305 (1) 166110 nt
    Select Tool
    Polypeptide UniProtKB:Q503E4 (1) 397 aa
    Sequence Information (all 19)
    ORTHOLOGY for gja2 ( Chr: 5 )
    CITATIONS (28)