gja2

ID

ZDB-GENE-040406-2

Name

gap junction protein, alpha 2

Symbol

gja2 Nomenclature History

Previous Names

cx39.9 (1)
cx46l (1)
zgc:110668

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable gap junction channel activity. Acts upstream of or within cell communication by electrical coupling and slow-twitch skeletal muscle fiber contraction. Predicted to be located in gap junction and plasma membrane. Predicted to be part of connexin complex. Is expressed in several structures, including eye; kidney; liver; musculature system; and spinal cord.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu255 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Hirata et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gja2 Human Ortholog

No data available

Associated With gja2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017990	Connexin, conserved site
Domain	IPR013092	Connexin, N-terminal
Domain	IPR019570	Gap junction protein, cysteine-rich domain
Family	IPR000500	Connexin
Homologous_superfamily	IPR034634	Connexin, C-terminal
Homologous_superfamily	IPR038359	Connexin, N-terminal domain superfamily