ZFIN ID: ZDB-GENE-040329-1
Gene Name: arylalkylamine N-acetyltransferase 1
Gene Symbol: aanat1    Nomenclature History

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Previous Name: aanat1a (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Exhibits acetyltransferase activity. Predicted to be involved in circadian rhythm and response to light stimulus. Predicted to localize to cytoplasm. Is expressed in brain; epiphysis; ovary; and retina. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome. Orthologous to human AANAT (aralkylamine N-acetyltransferase).
Genome Resources: Alliance (1),  Gene:393677 (1),  Ensembl(GRCz11):ENSDARG00000036567 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 3 publications
Directly Submitted Expression Data: 5 figures (7 images) from Thisse et al., 2004 [MGC:73074]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct823 Small Deletion Unknown Frameshift, Premature Stop CRISPR
sa33859 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-aanat1 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aanat1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH aanat1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process circadian rhythm (more)
    Cellular Component cytoplasm (more)
    Molecular Function acetyltransferase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aanat1-201 (1)    Ensembl 1621
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aanat1 No data available
    MARKER RELATIONSHIPS
    aanat1 Contained in: [BAC] CH73-274C18 (1)
    aanat1 Encodes: [cDNA] MGC:73074 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200704 (1) 1613 nt
    Genomic GenBank:CU062632 (1) 88714 nt
    Select Tool
    Polypeptide UniProtKB:Q6V7J8 (1) 204 aa
    Sequence Information (all 10)
    ORTHOLOGY for aanat1 ( Chr: 6 )
    CITATIONS (33)