ZFIN ID: ZDB-GENE-040324-1
Gene Name: hypocretin (orexin) neuropeptide precursor
Gene Symbol: hcrt
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have hypocretin receptor binding activity; involved in several processes, including circadian sleep/wake cycle, wakefulness, multicellular organismal response to stress, and response to  ...
GENE EXPRESSION
All Expression Data: 35 figures from 23 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zf719 Small Deletion Exon 2 Unknown TALEN
Targeting reagents:
PHENOTYPE
Data: 2 figures from Nishimura et al., 2015
Observed in:
DISEASE ASSOCIATED WITH hcrt HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
narcolepsy ?Narcolepsy 1 161400
DISEASE ASSOCIATED WITH hcrt VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to starvation (more)
Molecular Function hypocretin receptor binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001704 (1)
  • Pfam:PF02072 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hcrt-201 (1) 483
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM hcrt
    MARKER RELATIONSHIPS
    hcrtContained in: [BAC] CH211-210G13 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077392 (1) 487bp
    Genomic GenBank:BX005093 (1) 155392bp
    Select Tool
    Polypeptide UniProtKB:F1QMC8 (1) 129aa
    Sequence Clusters UniGene:95190 (1)
    Sequence Information (all 13)
    OTHER hcrt GENE PAGES
  • Alliance (1)
  • Gene:613239 (1)
  • VEGA:OTTDARG00000027133 (1)
  • Ensembl(GRCz11):ENSDARG00000070932 (1)
  • ORTHOLOGY for hcrt (Chr: 3)
    CITATIONS (57)