Gene
uros
- ID
- ZDB-GENE-040323-2
- Name
- uroporphyrinogen III synthase
- Symbol
- uros Nomenclature History
- Previous Names
-
- wu:fd13d11
- zgc:110240
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have uroporphyrinogen-III synthase activity. Predicted to be involved in heme biosynthetic process and uroporphyrinogen III biosynthetic process. Human ortholog(s) of this gene implicated in cutaneous porphyria. Is expressed in hematopoietic system; mesoderm; and notochord. Orthologous to human UROS (uroporphyrinogen III synthase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912557 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cutaneous porphyria | Alliance | Porphyria, congenital erythropoietic | 263700 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tetrapyrrole biosynthesis, uroporphyrinogen III synthase | Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily | Uroporphyrinogen-III synthase |
|---|---|---|---|---|
|
UniProtKB:Q568K6
|
262 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available