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General Information
ZIRC
ZFIN ID: ZDB-GENE-040323-2
Gene Name: uroporphyrinogen III synthase
Gene Symbol: uros
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: wu:fd13d11, zgc:110240

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have uroporphyrinogen-III synthase activity; predicted to be involved in heme biosynthetic process and uroporphyrinogen III biosynthetic process; orthologous to human UROS  ...
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 4 figures (5 images) from Thisse et al., 2004 [IMAGE:6912557]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la018325Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35380 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH uros HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    cutaneous porphyria Porphyria, congenital erythropoietic 263700
    DISEASE ASSOCIATED WITH uros VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process tetrapyrrole biosynthetic process (more)
    Molecular Function uroporphyrinogen-III synthase activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003754 (1)
  • InterPro:IPR036108 (1)
  • InterPro:IPR039793 (1)
  • Pfam:PF02602 (1)
  • TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM uros No data available
    MARKER RELATIONSHIPS
    urosContains: [SNP] rs3728525 (1)
    urosEncodes: [EST] fd13d11 (1), IMAGE:6912557 (1) (order this)
    [cDNA] MGC:110240 (1) (order this), MGC:192012 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212828 (1)
    Genomic GenBank:CABZ01092166 (1) 1517bp
    Polypeptide UniProtKB:Q1ET39 (1) 262aa
    Sequence Clusters UniGene:24250 (1)
    Sequence Information (all 26)
    OTHER uros GENE PAGES
  • Alliance (1)
  • Gene:404731 (1)
  • Ensembl(GRCz11):ENSDARG00000027491 (2)
  • ORTHOLOGY for uros (Chr: 12)
    CITATIONS (29)