ZFIN ID: ZDB-GENE-040317-1
Gene Name: RAS (RAD and GEM)-like GTP-binding 1
Gene Symbol: rem1    Nomenclature History

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Previous Names: rem (1), horizin

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Exhibits calcium channel regulator activity. Predicted to be involved in negative regulation of high voltage-gated calcium channel activity and signal transduction. Predicted to localize to plasma membrane. Is expressed in nervous system; neural tube; segmental plate; and somite. Orthologous to human REM1 (RRAD and GEM like GTPase 1).
Genome Resources: Alliance (1),  Gene:394149 (1),  Ensembl(GRCz11):ENSDARG00000020544 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:56144]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH rem1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rem1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of high voltage-gated calcium channel activity (more)
Cellular Component membrane (more)
Molecular Function calcium channel regulator activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rem1-201 (1)    Ensembl 2143
rem1-202 (1)    Ensembl 1201
rem1-203 (1)    Ensembl 1013
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rem1 No data available
MARKER RELATIONSHIPS
rem1 Contained in: [BAC] DKEY-76P14 (order this)
rem1 Encodes: [cDNA] MGC:56144 (1), MGC:192469 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_201174 (1) 1912 nt
Genomic GenBank:AL831791 (1) 204498 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A076NAB2 (1) 298 aa
Sequence Information (all 22)
ORTHOLOGY for rem1 ( Chr: 11 )
CITATIONS (23)