Gene

rtn4r

ID
ZDB-GENE-040310-1
Name
reticulon 4 receptor
Symbol
rtn4r Nomenclature History
Previous Names
  • NgR
  • Nogo-66 receptor
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have Roundabout binding activity and heparin binding activity. Involved in axon guidance and peripheral nervous system neuron axonogenesis. Is expressed in nervous system. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human RTN4R (reticulon 4 receptor).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Brösamle et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rtn4r Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
schizophrenia Alliance {Schizophrenia, susceptibility to} 181500
Associated With rtn4r Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Cysteine-rich flanking region, C-terminal Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype
UniProtKB:Q6DH76 479
UniProtKB:A0A1Y7AKU3 7
UniProtKB:Q6X3Y5 479
UniProtKB:F1QPB1 479
UniProtKB:X1WD08 472
UniProtKB:A8BB22 459
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations