ZFIN ID: ZDB-GENE-040309-2
Gene Name: myogenic factor 6
Gene Symbol: myf6    Nomenclature History

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Previous Names: herculin (1), mrf4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in skeletal muscle tissue development. Predicted to localize to nucleus. Is expressed in several structures, including Rohon-Beard neurons; adaxial cell; fin; muscle precursor cell; and musculature system. Human ortholog(s) of this gene implicated in congenital structural myopathy. Orthologous to human MYF6 (myogenic factor 6).
Genome Resources: Alliance (1),  Gene:404208 (1),  Ensembl(GRCz11):ENSDARG00000029830 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2041 Point Mutation Unknown Premature Stop ENU
sa16975 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-myf6 N/A 2
    MO2-myf6 N/A 1
    MO3-myf6 N/A 1
    MO4-myf6 N/A 1
    DISEASE ASSOCIATED WITH myf6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myf6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process skeletal muscle tissue development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA myf6-201 (1)    Ensembl 720
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myf6 No data available
    MARKER RELATIONSHIPS
    myf6 Contained in: [BAC] CH211-91G3 (1)
    myf6 Encodes: [EST] eu833 (1)
    [cDNA] MGC:194919 (1), MGC:194926 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001003982 (1) 720 nt
    Genomic GenBank:BX537156 (1) 117987 nt
    Select Tool
    Polypeptide UniProtKB:B3DK75 (1) 239 aa
    Sequence Information (all 22)
    ORTHOLOGY for myf6 ( Chr: 4 )
    CITATIONS (52)