Gene

sh3bp4a

ID
ZDB-GENE-040303-3
Name
SH3-domain binding protein 4a
Symbol
sh3bp4a Nomenclature History
Previous Names
  • sh3bp4
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have GDP-dissociation inhibitor activity. Predicted to be involved in several processes, including negative regulation of GTPase activity; negative regulation of TOR signaling; and protein localization to lysosome. Predicted to localize to cytoplasm. Is expressed in several structures, including Kupffer's vesicle; lens placode; nervous system; optic primordium; and optic vesicle. Orthologous to human SH3BP4 (SH3 domain binding protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2005
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh3bp4a Human Ortholog
No data available
Associated With sh3bp4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000906 ZU5 domain
Domain IPR001452 SH3 domain
Domain IPR035456 SH3BP4, SH3 domain
Family IPR035455 SH3 domain-binding protein 4
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length SH3BP4, SH3 domain SH3 domain SH3 domain-binding protein 4 SH3-like domain superfamily ZU5 domain
UniProtKB:Q1LVQ2 965
UniProtKB:Q7T035 757
UniProtKB:Q7T034 936
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations