Gene

pofut1

ID
ZDB-GENE-040303-2
Name
protein O-fucosyltransferase 1
Symbol
pofut1 Nomenclature History
Previous Names
  • zgc:110472
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have peptide-O-fucosyltransferase activity. Predicted to be involved in Notch signaling pathway and fucose metabolic process. Human ortholog(s) of this gene implicated in Dowling-Degos disease. Orthologous to human POFUT1 (protein O-fucosyltransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pofut1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Dowling-Degos disease Alliance Dowling-Degos disease 2 615327
Associated With pofut1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019378 GDP-fucose protein O-fucosyltransferase
Family IPR039922 GDP-fucose protein O-fucosyltransferase 1
Domain Details Per Protein
Protein Length GDP-fucose protein O-fucosyltransferase GDP-fucose protein O-fucosyltransferase 1
UniProtKB:Q503K6 395
UniProtKB:Q7T028 395
UniProtKB:F1R676 395
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations