ZFIN ID: ZDB-GENE-040303-1
Gene Name: DAB adaptor protein 2
Gene Symbol: dab2
Sequence Ontology ID : SO:0000704

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Previous Name: sb:cb778

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in several processes, including Notch signaling pathway, angiogenesis, and regulation of signal transduction; orthologous to human DAB2 (DAB2, clathrin adaptor protein).
GENE EXPRESSION
All Expression Data: 43 figures from 29 publications
Directly Submitted Expression Data: 4 figures (14 images) from Thisse et al., 2001 [cb778]
  7 figures (12 images) from Thisse et al., 2005 [eu105]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45210 Point Mutation Unknown Missense, Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 5 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH dab2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dab2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Notch signaling pathway (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006020 (1)
  • InterPro:IPR011993 (1)
  • PROSITE:PS01179 (1)
  • Pfam:PF00640 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dab2-201 (1) 2444
    dab2-203 (1) 1723
    dab2-204 (1) 2336
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dab2 No data available
    MARKER RELATIONSHIPS
    dab2Contained in: [BAC] CH211-158M24 (1) (order this)
    dab2Encodes: [EST] cb778 (1) (order this), eu105 (1)
    [cDNA] MGC:77136 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_205757 (1) 2302bp
    Genomic GenBank:BX510649 (1) 189844bp
    Select Tool
    Polypeptide UniProtKB:B8A566 (1) 797aa
    Sequence Clusters UniGene:79878 (1)
    Sequence Information (all 27)
    OTHER dab2 GENE PAGES
  • Alliance (1)
  • Gene:404040 (1)
  • VEGA:OTTDARG00000023796 (1)
  • Ensembl(GRCz11):ENSDARG00000031761 (2)
  • ORTHOLOGY for dab2 (Chr: 5)
    CITATIONS (76)