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Gene

insig2

ID
ZDB-GENE-040202-1
Name
insulin induced gene 2
Symbol
insig2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable lipid binding activity. Predicted to be involved in several processes, including SREBP signaling pathway; SREBP-SCAP complex retention in endoplasmic reticulum; and cholesterol biosynthetic process. Predicted to act upstream of or within cholesterol metabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Orthologous to human INSIG2 (insulin induced gene 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With insig2 Human Ortholog
No data available
Associated With insig2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR025929 Insulin-induced protein family
Domain Details Per Protein
Protein Length Insulin-induced protein family
UniProtKB:Q8AV60 221
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations