ZFIN ID: ZDB-GENE-040122-4
Gene Name: ADP-ribosylation factor 2a
Gene Symbol: arf2a    Nomenclature History

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Previous Names: arf2, wu:fa19d10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have GTP binding activity. Predicted to be involved in Golgi to plasma membrane transport and intracellular protein transport. Predicted to localize to the Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARF1 (ADP ribosylation factor 1).
Genome Resources: Alliance (1),  Gene:399477 (1),  Ensembl(GRCz11):ENSDARG00000014763 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56000]
  1 figure (1 image) from Thisse et al., 2005 [eu87]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa45146 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arf2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arf2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular protein transport (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTP binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR005225 Small GTP-binding protein domain
    Family IPR006689 Small GTPase superfamily, ARF/SAR type
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arf2a-201 (1)    Ensembl 2600
    arf2a-202 (1)    Ensembl 603
    arf2a-203 (1)    Ensembl 760
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arf2a No data available
    MARKER RELATIONSHIPS
    arf2a Contained in: [BAC] CH211-205B11 (1)
    arf2a Encodes: [EST] eu87 (1), fa19d10 (1)
    [cDNA] MGC:56000 (1), MGC:77471 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201504 (1) 2616 nt
    Genomic GenBank:BX649288 (1) 145373 nt
    Select Tool
    Polypeptide UniProtKB:Q6NYD8 (1) 181 aa
    Sequence Information (all 14)
    ORTHOLOGY for arf2a ( Chr: 3 )
    CITATIONS (23)