ZFIN ID: ZDB-GENE-040120-2
Gene Name: cytochrome P450, family 2, subfamily P, polypeptide 9
Gene Symbol: cyp2p9    Nomenclature History

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Previous Names: cyp2j22, cyp2j2b (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension (multiple); myocardial infarction; and renal fibrosis. Is expressed in intestinal bulb; intestinal bulb primordium; and liver. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2).
Genome Resources: Alliance (1),  Gene:393592 (1),  Ensembl(GRCz11):ENSDARG00000022631 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (6 images) from Thisse et al., 2004 [MGC:63757]
Wild-type Stages, Structures: Pharyngula:Prim-15 (30.0h-36.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp2p9 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cyp2p9 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Family IPR008069 Cytochrome P450, E-class, group I, CYP2D-like
Conserved_site IPR017972 Cytochrome P450, conserved site
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cyp2p9-201 (1)    Ensembl 2328
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cyp2p9 No data available
MARKER RELATIONSHIPS
cyp2p9 Contained in: [BAC] DKEY-183N20 (1) (order this)
cyp2p9 Encodes: [cDNA] MGC:63757 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_200620 (1) 2347 bp
Genomic GenBank:BX322665 (1) 192437 bp
Select Tool
Polypeptide UniProtKB:Q5TZ85 (1) 496 aa
Sequence Information (all 11)
ORTHOLOGY for cyp2p9 ( Chr: 20 )
CITATIONS (27)