ZFIN ID: ZDB-GENE-040116-1
Gene Name: actin related protein 2/3 complex, subunit 1A
Gene Symbol: arpc1a    Nomenclature History

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Previous Name: wu:fk93e03

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation. Predicted to localize to Arp2/3 protein complex. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human ARPC1A (actin related protein 2/3 complex subunit 1A).
Genome Resources: Alliance (1),  Gene:394243 (1),  Ensembl(GRCz11):ENSDARG00000008383 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55434]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015219Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arpc1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arpc1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Arp2/3 complex-mediated actin nucleation (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arpc1a-201 (1)    Ensembl 1687
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arpc1a No data available
    MARKER RELATIONSHIPS
    arpc1a Contained in: [BAC] DKEY-33C3 (1) (order this)
    arpc1a Encodes: [EST] fk93e03
    [cDNA] MGC:55434 (1), MGC:191374 (1)
    arpc1a Has Artifact: [cDNA] MGC:172353 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201343 (1) 1708 nt
    Genomic GenBank:BX649559 (1) 143056 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZUQ0 (1) 370 aa
    Sequence Information (all 17)
    ORTHOLOGY for arpc1a ( Chr: 3 )
    CITATIONS (26)