Gene

insb

ID
ZDB-GENE-040113-2
Name
preproinsulin b
Symbol
insb Nomenclature History
Previous Names
  • zfins2 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have hormone activity. Predicted to be involved in glucose metabolic process. Predicted to localize to extracellular region. Is expressed in several structures, including blastomere; dermal bone; digestive system; kidney; and shield. Human ortholog(s) of this gene implicated in diabetic retinopathy; glucose metabolism disease (multiple); insulinoma; and pancreatic cancer. Orthologous to human INS (insulin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With insb Human Ortholog
No data available
Associated With insb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR022353 Insulin, conserved site
Domain IPR016179 Insulin-like
Family IPR004825 Insulin
Family IPR022352 Insulin family
Homologous_superfamily IPR036438 Insulin-like superfamily
Domain Details Per Protein
Protein Length Insulin Insulin, conserved site Insulin family Insulin-like Insulin-like superfamily
UniProtKB:Q2QAJ9 107
UniProtKB:A0A140LFX1 151
UniProtKB:F1QAE3 159
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations