Gene

nop56

ID

ZDB-GENE-040109-1

Name

NOP56 ribonucleoprotein homolog

Symbol

nop56 Nomenclature History

Previous Names

nol5a
NOP56 (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to have snoRNA binding activity. Involved in heart development. Predicted to localize to box C/D snoRNP complex and small-subunit processome. Is expressed in midbrain. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 36. Orthologous to human NOP56 (NOP56 ribonucleoprotein).

Genome Resources

Note

None

Expression

All Expression Data

1 figure from Recher et al., 2013

Cross-Species Comparison

High Throughput Data

No data available

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nop56 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
spinocerebellar ataxia type 36	Alliance	Spinocerebellar ataxia 36	614153

Associated With nop56 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002687	Nop domain
Domain	IPR012974	NOP5, N-terminal
Domain	IPR012976	NOSIC
Homologous_superfamily	IPR029012	Helix hairpin bin domain superfamily
Homologous_superfamily	IPR036070	Nop domain superfamily
Homologous_superfamily	IPR042239	Nop, C-terminal domain

Domain Details Per Protein

Protein	Length	Helix hairpin bin domain superfamily	NOP5, N-terminal	Nop, C-terminal domain	Nop domain	Nop domain superfamily	NOSIC
UniProtKB:Q6TEL4 InterPro	494
UniProtKB:G1K2N3 InterPro	110
UniProtKB:Q6PH34 InterPro	481
UniProtKB:Q6DRE5 InterPro	548
UniProtKB:Q5BKV5 InterPro	301
UniProtKB:E7EZW9 InterPro	142

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
aberrant processed transcript	nop56-201 (1) Ensembl	836 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
aberrant processed transcript	nop56-202 (1) Ensembl	1134 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	nop56-203 (1) Ensembl	2039 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nop56-003 (1) Ensembl	826 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nop56-004 (1) Ensembl	794 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nop56-005 (1) Ensembl	799 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	nop56-007 (1) Ensembl	1014 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Gene Tree: Ensembl

Citations